The Science Behind NOX15
There are two ways to produce nitric oxide (NO) in our bodies.
In one way, NO is produced when dietary nitrates are reduced to nitrite by bacteria and gastric acid. Another way to naturally create NO is by enzymatic reactions (nitric oxide synthase (NOS) enzyme) which converts L-arginine to NO.
nitric oxide
nitrate-nitrite-nitric oxide pathway
The main source of nitrate is found in our diet (especially in beetroot, carrot and leafy green vegetables).
Once nitrate is consumed by eating or drinking a beverage rich in nitrate, the bacteria in your oral cavity, commensal anaerobic bacteria reduce salivary nitrate to nitrite with the help of a powerful enzyme (the nitrate reductases enzyme).
In the gut, the gastric acidic milieu convert salivary nitrite to NO.
Nitrate and remaining nitrite is absorbed from the intestine into the circulation and can convert to bioactive NO in blood.
An active uptake of nitrate from the blood occurs in the salivary glands to start the process all over again.
nitric oxide
L-arginine-nitric oxide pathway
After supplementation or dietary intake, the amino acid citrulline is converted into arginine. During a cascade of enzymatic reactions, arginine is converted into nitric oxide, urea and ornithine.
Then ornithine can be converted into citrulline (to start the process all over again) and proline, a key amino acid needed for the biosynthesis of collagen.
Interestingly, the L‑arginine–NO pathway is oxygen dependent, whereas the nitrate–nitrite–NO pathway is gradually activated as oxygen tensions falls.
Our promise
Here at Biogenetika, we are dedicated to science. We ensure our formulations are made using only the purest, natural ingredients, and the latest scientific research. Our products are produced in an accredited facility with a Food Safe QLD license, Hazard Analysis Critical Control Point (HACCP) certified, 5 Star Food Business Accredited.
All our products contain ingredients that are scientifically proven and formulated by qualified naturopaths, dietitians and nutritionists.
ACAI BERRIES
Acai berries are packed with antioxidants, good fats for the heart, and fibre. This antioxidant-rich fruit has been used for centuries as a healing, immune-stimulating and energy-boosting food.¹
BEETROOT
Beetroot is rich in nitrate. Beetroot juice supplementation has been shown to decrease blood pressure, reduce the amount of oxygen needed during exercise and enhance athletic performance.²
CAMU CAMU
It is one of the most abundant sources of vitamin C. It has 60 times more vitamin C than oranges and its antioxidant content can assist in the management of chronic diseases and accelerated aging.³ Vitamin C has also shown to strengthen the blood vessels and improve endothelial function.⁴
The amazing world of amino acids
ARGININE
Discovered in 1895, arginine is a basic natural amino acid. It is also involved in many metabolic pathways within our body such as heart and brain function, immunity, and energy due to an increase in nitric oxide.⁹
ORNITHINE
Ornithine is an amino acid that is involved in the metabolism of carbohydrates, proteins, and lipids. In addition, ornithine can efficiently improve energy production and assist in the removal of a highly toxic molecule called ammonia.¹¹
CITRULLINE
Citrulline is a naturally occurring amino acid. It's known to enhance nitric oxide production, which supports improved blood flow, cardiovascular health, and exercise performance.¹⁴
The Superfood Blend
nox15 - Natural Vascular Dilator
NOX15 contains ingredients that are rich in nitrates. Nitrates can be converted into natural nitric oxide, a powerful vascular dilator. Nitric oxide been shown to increase blood flow, energy circulation and nutrient delivery.¹⁶⁻¹⁹